Which population is commonly considered for colorectal cancer screening?

• A. Adults aged 18 to 40
• B. Adults aged 60 to 85
• C. Adults aged 45 to 75
• D. Children under 12

Answer: (C)

The key idea is that colorectal cancer screening is recommended for adults at average risk within a specific age window, where the balance of benefits and harms is favorable. The commonly targeted group is adults aged 45 to 75 years. Starting at 45 allows detection of cancers and precancerous polyps earlier when screening can prevent cancer or catch it at a more treatable stage, and continuing through 75 preserves the mortality benefit while considering overall harms and resources. Younger adults (18–40) have a very low baseline risk, and screening is not routinely indicated for them. While some older individuals beyond 75 may consider screening, the standard routine recommendation is 45 to 75, with decisions beyond that age individualized.