Which grade indicates a moderate net benefit and should be offered?

• A. A
• B. B
• C. C
• D. D

Answer: (B)

The grading focuses on how the benefits balance with harms (net benefit) and how certain we are about that balance. When the net benefit is moderate, the USPSTF assigns a grade that means the service should be offered to patients. This reflects that the expected benefits justify offering the service, even though they aren’t as large as for a substantial benefit. So the grade indicating a moderate net benefit and the recommendation to offer aligns with providing the service to patients. Other grades describe stronger benefit (offered more assertively), smaller benefit with patient-specific decision-making, or insufficient evidence, which don’t match the moderate-net-benefit scenario.