Which are the five USPSTF recommendation grades?

• A. A, B, C, D
• B. A, B, C, D, I
• C. A, B, C, D, and I
• D. A, B, D, I

Answer: (B)

USPSTF grades preventive services using five categories: A, B, C, D, and I. A means high certainty of a substantial net benefit, and B means at least a moderate certainty of a substantial or moderate net benefit. C indicates a small net benefit or that the decision should be individualized based on patient context. D means the service is not recommended because harms outweigh benefits, and I indicates insufficient evidence to assess the balance of benefits and harms.

The correct option reflects this complete grading system: A, B, C, D, and I. The other choices omit one grade or otherwise don’t present the full set of categories, so they don’t accurately represent the USPSTF grading scheme. In practice, A and B lead to recommendations in favor, D to against, C invites discussion of options, and I signals that more evidence is needed.